Description
Monomethyl auristatin F (MMAF) is a synthetic peptide analog of the natural compound dolastatin 10. MMAF is a microtubule inhibitor, disrupts the formation of microtubules. MMAF is often used in conjunction with monoclonal antibodies as part of an antibody-drug conjugate (ADC) therapy.
Specifications
|
Cat.No. |
31904ES60/31904ES80 |
|
Size |
100 μg/1 mg |
|
Source |
Monoclonal anti-MMAF antibody, is produced from a hybridoma which was obtained from a mouse immunized with MMAF. |
|
Buffer |
1×PBS, pH7.4. |
|
Type |
Monoclonal Antibody |
|
Isotype |
IgG1 |
|
Host |
Mouse |
|
Concentration |
1 mg/mL |
|
Purity |
＞92% as determined by reduced SDS-PAGE ＞98% as determined by non-reduced SDS-PAGE > 91% as determined by SEC-HPLC |
|
Activity |
EC50=13 ng/mL by ELISA |
|
Application |
ELISA |
Storage
This product should be stored at -25~-15℃ for one year, do not freeze.
Notes
- This product is for research use only.
- Please operate with lab coats and disposable gloves, for your safety.
Data
SDS-PAGE
Anti-MMAF mouse mAb on SDS-PAGE under reduced condition. The purity is 92.3%；
Anti-MMAF mouse mAb on SDS-PAGE under non-reduced condition. The purity is 98.5%.
SEC-HPLC
The purity of Anti-MMAF mouse mAb is 91.2% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-MMAF mouse mAb is 13 ng/mL.