RNase inhibitors are a class of substances that can inhibit RNase activity. Common RNase inhibitors include Diethyl Pyrocarbonate (DEPC), Guanidine Isothiocyanate, Ribonucleoside Vanadyl Complexes (RVC), and protein inhibitors of RNase (RNasin). Among them, DEPC and guanidine isothiocyanate has certain toxicity, and the RVC has an inhibitory effect on PCR polymerase, which is not conducive to subsequent experiments. RNasin is not toxic and is a non-competitive inhibitor of RNase, which can bind to various RNases to inactivate them. Recombinant murine RNase inhibitors supplied by Yeasen do not contain 2 oxidation-sensitive cysteines which are contained in human-origin RNase inhibitors. Therefore, murine RNase inhibitor has high anti-oxidation activity and is more stable for low DTT experiments.